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Bovine tuberculosis: Florid, granulomatous lymphadenitis in a buffalo (wtbflor3)

Almost all the normal tissue from this lymph node has been replaced by a tan-coloured granulomatous inflammatory reaction.  Note the absence of a capsule around the granuloma, and the lack of any form of necrosis.  In these type of lesions, few, if any, acid-fast bacteria are seen in histological sections of the tissue, or in tissue smears made for diagnostic purposes.

Nick Kriek